Polymyositis Masquerading as Motor Neuron Disease
نویسندگان
چکیده
منابع مشابه
Hypothyroidism masquerading as polymyositis.
A group of patients is described who presented with proximal muscle weakness and elevated muscle enzymes. They were initially believed to have polymyositis and one of them was even treated as such over a long period of time. The patients were subsequently found to have hypothyroidism and responded well to thyroid hormone replacement. Hypothyroidism should always be considered in the differentia...
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A 66 year old HIV infected male heavy smoker presented with arthralgia, myalgia, and weight loss which was originally ascribed to nucleoside induced mitochondrial toxicity. Despite withdrawal of antiretroviral therapy a proximal myopathy developed. Further investigation excluded malignancy. Polymyositis was diagnosed on muscle biopsy. The patient recovered completely with oral prednisolone. Thi...
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A 63-year-old lady presented in May 2010 with a three-month history of fever, weight loss, night sweats and a widespread rash. The initial diagnosis was a relapse of polymyositis. She had anti Jo-1 antibody-related polymyositis diagnosed in 1993 on clinical, serologic and electromyologic evidence. She had been treated with ≥15 mg prednisolone since 1993 and weekly oral methotrexate 15 mg since ...
متن کاملMotor Neuron Disease
Neurologists in the 19th century recognized that muscle weakness could be due to primary disorders of muscle or secondary to loss of neuromuscular integrity, as happens when peripheral nerves are cut or when motor neurons degenerate. Furthermore, it was observed that there are forms of motor neuron degeneration which selectively affect upper motor neurons or lower motor neurons. A combination o...
متن کاملAssessing motor neuron disease.
Hadjikoutis and Wiles draw attention to a number of circumstances in which the serum chloride and bicarbonate can be misleading. They do not mention that they will also be misleading if they are measured when hypercapnia is increasing or decreasing. An exacerbation of hypercapnia will take 4 – 6 days to raise the serum bicarbonate and lower the serum chloride to new steady levels. 1 How long it...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2003
ISSN: 0003-9942
DOI: 10.1001/archneur.60.7.1001